Soleno Therapeutics (SLNO) became a market focus during Monday's early trading session, with its shares rising sharply by 26% in pre-market activity driven by deal negotiation reports. Reports indicated that Neurocrine Biosciences is in advanced talks to acquire the company, with a potential valuation exceeding $2.5 billion, or a price per share in the low-to-mid $50 range. If finalized, the deal would grant Neurocrine access to Soleno's treatment for Prader-Willi syndrome, which analysts project could achieve peak annual sales of $2.3 billion. Other individual stocks also displayed a more positive market tone. Twilio (TWLO) gained approximately 3% after Jefferies upgraded the stock to "buy" and set a $160 price target, citing its stronger positioning in voice AI and improving fundamentals. Netflix also rose about 2% following an upgrade to "buy" by Goldman Sachs, which highlighted improved growth visibility, margin expansion potential, and the possibility of share repurchases.
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