US IPO Window Reopens: From AI Chips to Precision Medicine-New Listings Guide
The US IPO market is springing back to life as geopolitical tensions ease. Last Friday (April 17), precision proteomics leader $Alamar Biosciences(ALMR)$ surged over 34% on its Nasdaq debut, while emergency medical giant GMR Solutions (GMRS) officially filed its prospectus. This week, AI chip unicorn Cerebras (CBRS), mobile ad platform Liftoff Mobile (LFTO), and neuro-rehab device maker Mobia Medical (MOBI) joined or rejoined the pipeline. Here is a comprehensive breakdown of what each company does, its financials, and its investment potential.
Friday’s Benchmark: Alamar Biosciences (ALMR)
Alamar priced its IPO at $17 per share and opened at $22.91, delivering a 34% first-day pop and closing with a market cap of approximately $1.43 billion. The company upsized its offering to 11.25 million shares, raising $191 million in total proceeds.
What it does: Alamar develops the proprietary NULISA platform, enabling ultra-sensitive detection of protein biomarkers in blood for early disease screening—particularly in Alzheimer’s and Parkinson’s research.
Financials & Valuation: Revenue nearly tripled to $74.2 million in 2025 (up 195% YoY), while the net loss narrowed to $29.8 million from $47.1 million in 2024. At its current valuation, Alamar trades at roughly 19x trailing P/S, reflecting a clear market premium for early-detection proteomics technology.
The Four New Filers: At a Glance
|
Company |
Ticker |
Sector |
2025 Revenue |
Target Raise |
Valuation / Market Cap |
Key Catalyst |
|---|---|---|---|---|---|---|
|
Cerebras |
CBRS |
AI Chips / Datacenter |
$510M |
~$2.0B |
~$23B (Series H) |
OpenAI $10B+ contract; first Nvidia alternative to go public |
|
GMR Solutions |
GMRS |
Emergency Medical Services |
$5.74B |
$1.0B |
TBD |
Defensive infrastructure; $206M net profit |
|
Liftoff Mobile |
LFTO |
AI Mobile Advertising |
$686M |
$762M |
Up to $5.17B |
1.4B daily active users; 43% core ad revenue growth |
|
Mobia Medical |
MOBI |
Neuro-Rehab Devices |
$32M |
$100M |
TBD |
Only FDA-approved PaVNS for stroke; $30B TAM |
1. Cerebras Systems (CBRS) — The $23B "Nvidia Challenger"
Cerebras publicly refiled its S-1 on April 17 after withdrawing its 2024 application due to CFIUS review. It targets a Nasdaq listing in May 2026.
What it does: Cerebras builds the Wafer Scale Engine (WSE-3), a processor that spans an entire 300mm silicon wafer. With 4 trillion transistors and 900,000 cores, it is physically 56x larger than Nvidia’s H100 and claims 21x performance at one-third the cost for certain AI workloads.
Financials & Valuation: The company generated $510 million in revenue in 2025 (+76% YoY), turning to a GAAP net income of $87.9 million (though it still posted a non-GAAP net loss of $75.7 million). After a $1 billion Series H in February, its valuation stands at $23 billion, with the IPO targeting roughly $2 billion in proceeds led by Morgan Stanley.
The OpenAI Contract: On April 16—one day before the IPO filing—OpenAI committed to a multi-year compute deal reportedly worth more than $10 billion, covering up to 750 megawatts of AI processing power through 2028. Some reports value the three-year agreement at over $20 billion. This fundamentally reshapes Cerebras’s customer-concentration risk: UAE-based G42 fell from 87% of revenue in H1 2024 to just 24% in 2025.
Investment Angle: Cerebras would be the first pure-play, non-Nvidia AI chipmaker to hit public markets in this infrastructure cycle. However, at $23 billion, it trades at roughly 45x trailing sales. The bull case depends on flawless execution of the OpenAI contract and successful diversification beyond Middle Eastern clients.
2. GMR Solutions (GMRS) — A $5.7B Revenue Defensive Play
GMR filed on Friday for a NYSE listing, targeting up to $1 billion in proceeds.
What it does: Formed in 2018 from the merger of Air Medical Group Holdings and American Medical Response, GMR is the leading US provider of emergency medical services (EMS) and alternate-site care. It operates air and ground ambulance networks, serving as a critical entry point into the healthcare system across urban and rural communities.
Financials: The company booked $5.74 billion in revenue for 2025 with a net profit of $206.2 million , making it the largest revenue generator among this cohort by a wide margin.
Investment Angle: Unlike the high-growth, high-burn tech names, GMR offers a defensive, infrastructure-like exposure to US healthcare. Its profitability and recession-resistant demand profile may attract institutional capital seeking stability amid macro uncertainty.
3. Liftoff Mobile (LFTO) — AI Advertising at 1.4B Daily Users
Liftoff refiled its IPO just two months after withdrawing in February, demonstrating management’s urgency to capitalize on the reopened window.
What it does: Formed from the 2021 merger of Liftoff and Vungle (both Blackstone-owned), the company provides AI-powered user acquisition and ad monetization software for mobile apps. Its SDK is integrated into over 140,000 apps, reaching approximately 1.4 billion daily active users and serving 1,000+ marketers globally.
Financials: Revenue reached $686 million in 2025, with core advertising revenue growing 43% YoY in the nine months ended September 30, 2025. The company significantly narrowed its net loss to $23.1 million (from $48.2 million in the prior year). It now seeks to raise up to $762 million at a valuation of up to $5.17 billion.
Investment Angle: Liftoff is a direct peer to $AppLovin Corporation(APP)$ in the AI-driven mobile ad space. The 1.4B user reach provides a formidable data moat, but investors should benchmark its pricing against AppLovin’s current multiples and monitor privacy-policy headwinds.
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4. Mobia Medical (MOBI) — The "Small but Moated" Neuro-Rehab Play
Mobia filed on April 17 for a Nasdaq listing, targeting $100 million.
What it does: Mobia’s flagship product, Vivistim, is the first and only FDA-approved Paired Vagus Nerve Stimulation (PaVNS) system for chronic ischemic stroke survivors with moderate-to-severe upper limb impairment. The implantable device stimulates the vagus nerve during rehabilitation to enhance neuroplasticity.
Financials: Revenue doubled to $32 million in 2025 (from $15.6 million in 2024). Management estimates a $30 billion addressable market in the US, with roughly 1 million of the 4 million chronic stroke survivors eligible for therapy.
Investment Angle: Mobia is a classic high-growth medtech story: FDA exclusivity, 105% revenue growth, and an unmet clinical need. Like Alamar, it commands a scarcity premium. The IPO is led by BofA Securities, J.P. Morgan, and Goldman Sachs.
Market Signal: IPOs as M&A Currency
On the same day it listed (April 17), digital asset financial services firm Diginex announced a $1.5 billion all-stock acquisition of AI customer-intelligence firm Resulticks (2025 revenue ~$150 million). This underscores a broader trend: newly public companies are immediately leveraging their stock currency to buy AI/data capabilities. For IPO investors, this means the post-listing growth story may include aggressive M&A-driven expansion into enterprise AI agents.
Investor Strategy: How to Play This Wave
For IPO Flippers: Alamar’s 34% debut proves that medtech with FDA exclusivity or platform scarcity (NULISA, Vivistim) commands immediate demand. Mobia, with 105% growth and sole FDA approval in its niche, is the closest comp.
For Growth Investors: Cerebras is the headline act. At $23 billion, the market is pricing in near-perfect execution of the OpenAI contract. Watch for two signals post-IPO: (1) the pace at which non-G42 revenue scales, and (2) whether gross margins expand as wafer-scale production ramps.
For Defensive Allocators: GMR Solutions offers a rare combination of scale ($5.7B revenue), profitability ($206M net income), and non-cyclical demand. It is the only "infrastructure-grade" name in this cohort.
For Ad-Tech Speculators: Liftoff’s 1.4B DAU footprint and 43% core revenue growth are compelling, but its valuation (up to $5.17B, or ~7.5x sales) requires a continued bull market in mobile app spending to sustain.
Bottom Line
This week’s IPO pipeline sends a clear signal: the market is willing to pay steep premiums for AI infrastructure (Cerebras) and precision medicine (Alamar, Mobia), while also making room for profitable infrastructure (GMR) and scaled ad-tech (Liftoff). The window is open—but as Alamar’s 34% pop and Cerebras’s $23 billion valuation show, the bar for execution has never been higher. Choose your exposure based on risk tolerance, not just headline hype.
Disclaimer: Investing carries risk. This is not financial advice. The above content should not be regarded as an offer, recommendation, or solicitation on acquiring or disposing of any financial products, any associated discussions, comments, or posts by author or other users should not be considered as such either. It is solely for general information purpose only, which does not consider your own investment objectives, financial situations or needs. TTM assumes no responsibility or warranty for the accuracy and completeness of the information, investors should do their own research and may seek professional advice before investing.

